This book is a collection of information about applying CRISPR-Cas systems for genome editing in plants. The main focus of this book is to address the recent advances and future prospects of CRISPR-Cas technology in crops.

This book reviews all important aspects of plant genome editing to shed new light on these genome editing technologies together in crop improvement and sustainable agriculture. The book is divided into three areas: the first of which reinterprets plant genome studies from an overview perspective, examining the safety and risk assessment of plants as well as breeding-related outcomes. The second area discusses recent advances in the understanding of crop improvement. A wide range of plant stress tolerance in relation to plant genome editing is then addressed, before turning attention to specific species approaches including rice, maize, wheat, and soybean. The entire book is devoted to an updated knowledge of plant genome editing technologies from all aspects of plant biology and agronomy as we move toward advancements in sustainable life research. The book will be highly recommended for agriculture biologists, agronomists, plant pathologists, and all related research areas.

This book provides a comprehensive overview of the molecular basis of developmental and stem cell regulation. It revisits some of the classical models of developmental biology and puts them in context with the findings of modern stem cell research and developmental biology.

"Water is life!" All active cellular systems require water as the medium and solvent of their metabolic activities. Hydrophobic compounds and structures, which tend to exclude water, though providing inter alia excellent sources of energy and a means of biological compartmentalization, present problems of cellular handling, poor bioavailability and, in some cases, toxicity. Microbes both synthesize and exploit a vast range of hydrophobic organics, especially petroleum oil hydrocarbons and industrial pollutants, and the underlying interactions not only have major consequences for the lifestyles of the microbes involved, but also for biogeochemistry, climate change, environmental pollution, human health and a range of biotechnological applications. The aim of this handbook is to be the definitive resource of current knowledge on the diverse and multifaceted aspects of these interactions, the microbial players, and the physiological mechanisms and adaptive strategies characteristic ofthe microbial lifestyle that plays out at hydrophobic material: aqueous liquid interfaces.

This edited book provides comprehensive coverage of the recent advances in genetics and genomics of high-altitude crops (HACs). This book also assists in understanding the genomic adaptation to the environmental extremes at high altitude conditions.

Vols 1 and 2 contain 57 papers in the Special Issue of 'Plant Genomics 2009' and cover a wide range of topics, highlighting the significant progress that has been made in recent years in our understanding of the genetics and genomics of plants' growth, development, and stress responses. These studies provide valuable insights into the potential applications of genomic tools and technologies for crop improvement and sustainable agriculture, as well as fundamental questions about the evolution and function of plant genes and genomes.

Vols 1 and 2 contain 57 papers in the Special Issue of 'Plant Genomics 2009' and cover a wide range of topics, highlighting the significant progress that has been made in recent years in our understanding of the genetics and genomics of plants' growth, development, and stress responses. These studies provide valuable insights into the potential applications of genomic tools and technologies for crop improvement and sustainable agriculture, as well as fundamental questions about the evolution and function of plant genes and genomes.

This edited book support Sustainable Development Goal 2 (SDG 2): Zero Hunger. This book summarizes the contribution of genetic engineering for sustainable crop improvement toward global food and health security, climate resilience and economic growth. The book acts as a compendium of research reports on recent developments in the arena of cisgenics or transgenics or genome editing of crop plants for tolerance to biotic or abiotic stresses, introgression of value-added traits, molecular pharming etc. Sustainable crop productivity, yield and nutrition are the major constrain for food and nutritional security for the human population especially, in developing countries where arable land per capita is shrinking while the human population is steadily increasing. Zero hunger and achieving food security is the top priority of the United Nations development goals. This book explains various methods of genetic transformation such as transgenic, cisgenic, and genome editing for crop improvement. It also encompasses the advantages of genetic engineering in plants and their scope for sustainable crop improvement. The importance, limitations, challenges, GM biosafety regulations, recent advancements and future prospects of GM crops are covered in various chapters. This book is of interest to teachers, researchers, plant tissue culturists, GM crop experts, research scholars, academicians, plant breeders, policymakers etc. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences. National and international agricultural scientists and policymakers will also find this to be a useful read.

This book evolved from the editors strong belief that the information and new developments that were evolving from the rapidly growing field of genomics and that are happening primarily in the developed world have not happened at a parallel rate in the developing world. One would have hoped that by now the technologies and approaches would have been adapted on a far greater scale. In addition to this, the associated information is not always easily accessible, and is not disseminated in a format that can become a useful reference for scientists, students and others who reside in developing countries.

This edited book is a compilation of information on existing frontier technologies in agriculture, such as driving modernized crop improvement programs via digitalization, mechanization and automation, artificial intelligence, speed breeding. The major focus of the book is on the technologies related to genetic gain, nutrition and food safety. Agriculture is core to industry as well as human civilization and sustainability of the society.

This textbook examines the fundamental principles of microbial metabolism and how a microbe's ecology is intrinsically interwoven with and a consequence of its metabolism. Further, it answers many questions frequently asked by students, such as: What are the mechanistic connections between simple phenotypic traits, ecological patterns and microbial metabolism and diversity? In the process, readers will be introduced to essential topics like metabolism and metabolic pathways, flux of energy and nutrients, genome size and fitness, competition, selection and drift.

This book is a compilation of protocols developed through a Coordinated Research Project of the Joint FAO/IAEA Center of Nuclear Techniques in Food and Agriculture, specifically focused on mutation breeding for resistance to Striga. The book consists of three sections; (i) a general introduction on Striga biology and impact and mutagenesis in cereal crops; (ii) protocol chapters focusing on field, screenhouse and laboratory screening and diagnostic for resistance to Striga asiatica and S. hermonthica in sorghum, upland rice and maize, and; (iii) efficiency enhancing technologies such as rapid crop cycling, doubled haploid production and genomics for mutation discovery and marker development. These chapters were written by well recognized experts in Striga biology and physiology, and cereal breeders. The book is intended to serve as a unique reference and guide for plant breeders and geneticists engaged in breeding for resistance to Striga in cereals.

This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.

The fascinating area of molecular medicine provides a molecular and cellular description of health and disease. Starting with the understanding of gene regulation and epigenetics, i.e., the interplay of transcription factors and chromatin, this book will provide an fundamental basis of nearly all processes in physiology, both in health as well as in most common disorders, such as cancer, diabetes as well as in autoimmune diseases. Most non-communicable human diseases have a genetic (= inherited) as well as an epigenetic component. The later one is based on our lifestyle choices and environmental exposures. Many common diseases, such as type 2 diabetes, can be explained only to some 20% via a genetic predisposition. We cannot change the genes that we are born with but we can take care of the remaining 80% being primarily based on our epigenome. Therefore, there is a high level of individual responsibility for staying healthy. Thus, not only biologists and biochemists should be aware of this topic, but all students of biomedical disciplines will benefit from being introduced into the concepts of molecular medicine. This will provide them with a good basis for their specialized disciplines of modern life science research.

This book is an update of genome editing techniques applied to a range of plants. We discuss the latest techniques and applications to cereals, roots and tubers, oilseed crops, fruit and forest trees, vegetables, legumes and algae including resistance to biotic and abiotic stresses, improved quality, drug production, yield and adaptation to climate change. The regulations in different countries worldwide, the patentibility and the perception by society of the applications of new genomic techniques are examined. This book is written by a multidisciplinary and multisectoral collective of high-profile scientists and other experts belonging to the COST Action network PlantEd, which is mainly European but with contributions from American, Australian, Canadian, Chinese, Indian, Iranian, Pakistani and Peruvian scientists. The book is aimed at a wide audience consisting of students, academics, private and public breeders, other actors in the food and bioeconomy value chains and policy and law makers.