"Chagas Disease: Basic Investigations and Challenges" ed. by Veeranoot Nissapatorn, Helieh S. Oz

This book contains chapters of significant and updated materials on what we know and what we lack and need in better understanding of Trypanosoma cruzi - a parasite that never dies - and the consequences of Chagas disease as one of the most important neglected parasitic diseases threatening the global health and wellbeing.

The book is intended to increase the readers' enthusiasm to explore the four sections of the contents: Section 1 begins with biochemistry, pathophysiology, histo-immunological study, and findings to assist in the diagnosis; Section 2 further investigates the role of vector in propagation of the parasite, the intensity on epidemiology, and the severity on clinical aspects, which help us to be well perceived on the course of disease; Section 3 is seeking beyond modern medicine and what lays in the nature that helps fight against this parasite; and the last section, Section 4, deals with the impacts of public health problem and the control strategies on Chagas disease.

Contents
1. Chagas Disease and Its Global Impacts
2. Biochemical, Cellular, and Immunologic Aspects during Early Interaction between Trypanosoma cruzi and Host Cell
3. Antiparasitic Mechanisms of the Human Placenta
4. The Mouse Model as a Tool for Histological, Immunological and Parasitological Studies of Trypanosoma cruzi Infection
5. Transmitter Insect of Chagas Disease in Northwest Mexico: A Comparative Study of the Cuticular Hydrocarbons Profile of Three Populations of Triatoma rubida: Peridomestic, Domestic
6. Eco-Epidemiology of Chagas Disease in Chile
7. Chagas Cardiomyopathy: Role of Sustained Host-Parasite Interaction in Systemic Inflammatory Burden
8. Efficacy and Safety of Chagas Disease Drug Therapy and Treatment Perspectives
9. New Approaches for Chagas’ Disease Chemotherapy
10. Slowed Development of Natural Products for Chagas Disease, how to Move Forward?
11. Silent Information Regulator 2 from Trypanosoma cruzi Is a Potential Target to Infection Control



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